Description
Mega IgG 2000 is a dairy-free immunoglobulin concentrate that supports healthy digestion and maintains healthy gut barrier function. Unlike other milk-derived immunoglobulins on the market, Mega IgG2000 is derived from bovine serum, making it lactose-free, casein-free, and β-lactoglobulin-free.
This unique alternative to bovine colostrum supports a healthy mucosal immune system by maintaining healthy gut barrier function. The serum immunoglobulin in Mega IgG 2000 has been the subject in over 10 published human clinical trials.*
In a randomized, double-blind, placebo-controlled, pilot study evaluating SBI in children 8-18 y with d-IBS, we collected stool number, abdominal pain, and stool type for 1 wk. We assigned patients at a ratio of 2:1 to SBI 5 gm BID or placebo for 3 wk. Patients and parents completed Pediatric Quality of Life Inventory for Gastrointestinal Symptoms (PedsQOL), the Pediatric Functional Disability Index (FDI), complete blood counts and serum chemistries at the start and end of treatment. Fifteen patients (9 SBI, 6 placebo) completed the study. Both groups reported reductions in stools/wk and abdominal pain, and improved stool form. There was a trend for fewer stools in the SBI group compared to placebo. FDI and PedsQOL scores improved.in the SBI group, but not placebo. No serious adverse events occurred. SBI was safe in children with d-IBS, with improvement in symptoms.
Serum‐derived bovine immunoglobulin (SBI) is a protein isolate rich in immunoglobulins for oral administration to improve immune health. SBI reduces inflammation by binding and neutralizing a variety of inflammatory antigens, improving gut epithelial barrier integrity, and maintaining gut homeostasis. In this study, fluorescence spectroscopy was used to demonstrate and quantify the binding of SBI to the fungal mycotoxins, aflatoxin G1 (AFG1) and aflatoxin B2 (AFB2). Calculated binding constants reveal SBI binds with both AFG1 and AFB2 in a dose dependent manner, likely through immunoglobulin‐aflatoxin interactions.
Size: 120 Capsules / 60 grams (powder)
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease.