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Nattokinase is a powerful enzyme used to support normal blood flow, circulation, and blood pressure levels. Maintaining healthy blood circulation and balanced coagulation is a key part of supporting cardiovascular health. Fibrinolytic enzymes, such as plasmin, produced in the endothelial cells are responsible for ensuring proper blood flow. However, the production of these enzymes decreases with age, which can result in increased fibrin levels. In vitro studies have highlighted that nattokinase triggers the release of substances that lead to the production of other important enzymes, like plasmin, which help regulate fibrin formation. It also inhibits a key enzyme that causes arterial dilation to help maintain healthy blood pressure levels and can generate tissue plasminogen activators helping to promote blood flow.
Maintaining healthy blood circulation and balanced coagulation is a key part of supporting cardiovascular health. Fibrinolytic enzymes, such as plasmin, produced in the endothelial cells are responsible for ensuring proper blood flow. However, production of these enzymes decreases with age, which can result in increased fibrin levels. Nattokinase also inhibits a key enzyme resulting in arterial dilation to help maintain healthy blood pressure levels, and can generate tissue plasminogen activators helping to promote blood flow. Because it is a highly purified extract derived from soybeans, supplementing nattokinase differs from consuming soybeans in that nattokinase escapes the typical breakdown by digestive enzymes, and is absorbed and taken into the body directly from the small intestine to exert its effects in the plasma.
Discovered by Dr. Hiroyuki Sumi, nattokinase has been shown to help keep blood flowing normally. In a study on the effect of nattokinase on blood flow in the common carotid artery, animals treated with nattokinase regained 62% of their blood flow, while animals given plasmin regained 15.8%, and 0% was regained with elastase. Researchers concluded that in this in vivo model, the circulation supporting activity of nattokinase was stronger than that of plasmin or elastase.6,7 Other in vitro studies revealed nattokinase caused a significant, dosedependent decrease of red blood cell aggregation and lowshear viscosity, effects which were evident at concentrations similar to those achieved with in vivo animal trials. Researchers have also confirmed the presence of unique compounds that inhibit angiotensin converting enzymes (ACE) within nattokinase, which supports healthy arterial blood pressure. In a recent eight-week, randomized, double-blind, placebo-controlled trial of 73 subjects given oral nattokinase supplementation, a healthy effect on blood pressure and blood flow was seen.
While many of the agents involved in promoting healthy blood flow and coagulation either have limitations and/or serious side effects, this formulation of Nattokinase includes potent support activity that can last for more than 12 hours and is safe for long-term use.
Size: 60 Capsules
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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