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Coenzyme Q10 (CoQ10), also known as ubiquinone, is a proenzyme produced naturally within the body. CoQ10 plays a critical role in energy (ATP) production and is one of the most powerful known lipid-soluble antioxidants, protecting cells, organs and tissues from damage caused by oxidative stress and free radicals. CoQ-10 inhibits protein and lipid oxidation and protects mitochondrial DNA from oxidative damage. This CoQ-10 300mg formulation is highly concentrated for those that need to quickly and effectively increase levels of CoQ10. CoQ10 300mg is delivered in a proprietary oil-based formulation and includes natural vitamin E for enhanced absorption and maximum stability.
CoQ10 is a lipid-soluble antioxidant found in every cell in the body. CoQ10 is abundant in the mitochondrial membrane and plays an important role in the synthesis of adenosine triphosphate (ATP), a molecule of chemical energy upon which all cellular functions depend. The synthesis of ATP within the mitochondria is a multi-step series of biochemical reactions called the electron transport chain. As a coenzyme, CoQ10 is required for several enzymatic reactions required to produce cellular energy and to protect the body against free radicals produced during this process. To maintain energy production, mitochondrial CoQ10 is continuously recycled from ubiquinone, its ATP production state, to ubiquinol, its antioxidant state. After the age of 35 to 40 years, endogenous synthesis of CoQ10 begins to decline. CoQ10, an essential component of cellular energy production, has been shown to extend cell life and benefit high-energy systems, namely the cardiovascular, neurological, and immune systems. Supplementation with a highly concentrated, oilbased CoQ10 enables faster recovery of CoQ10 levels for those that have increased CoQ10 requirements including: those with drug-induced depletion, increasing age, or increased tissue demands. The safety of CoQ10 at high doses has been tested in a double-blind, placebo-controlled study. The findings in this study showed that CoQ10 was well tolerated and safe at a high intake (900 mg/day).
The body’s ability to produce and metabolize CoQ10 has been reported to decrease with age. CoQ10 deficiency may be caused by insufficient dietary intake of CoQ10, impairment in CoQ10
production, drug-induced CoQ10 depletion, gene mutations, and oxidative stress. HMG-CoA reductase is an enzyme required for the synthesis of cholesterol and CoQ10. Cholesterol lowering medications inhibit this enzyme in order to reduce cholesterol synthesis, but may also simultaneously deplete CoQ10 status. Thirteen controlled studies conducted between 1990-2004 demonstrated significant CoQ10 depletion, secondary to use of statin medications used to lower cholesterol levels. These studies demonstrated a range of 19-54% decrease in CoQ10 levels in patients on statin therapy. In the event of CoQ10 depletion, supplementation can improve CoQ10 status and help maintain optimal levels in the body.
Size: 60 caps
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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